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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX3
All Species:
6.36
Human Site:
Y307
Identified Species:
12.73
UniProt:
Q13761
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13761
NP_001026850.1
415
44356
Y307
T
S
R
F
H
H
T
Y
L
P
P
P
Y
P
G
Chimpanzee
Pan troglodytes
XP_001168112
361
38974
L254
S
R
F
H
H
T
Y
L
P
P
P
Y
P
G
A
Rhesus Macaque
Macaca mulatta
XP_001113682
501
52667
S393
Q
L
R
H
Q
A
S
S
P
G
Y
P
E
Q
Q
Dog
Lupus familis
XP_544492
414
44288
Y307
A
S
R
F
H
H
T
Y
L
P
P
P
Y
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q64131
409
43610
H302
M
P
A
S
S
R
F
H
H
T
Y
L
P
P
P
Rat
Rattus norvegicus
Q63046
450
48538
D316
P
T
L
P
S
I
S
D
P
R
M
H
Y
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232978
334
36473
A227
M
T
S
M
P
T
T
A
R
F
H
H
T
Y
L
Frog
Xenopus laevis
Q6PF39
462
50351
A354
G
M
S
A
M
T
S
A
T
R
Y
H
T
Y
L
Zebra Danio
Brachydanio rerio
NP_571679
424
45996
T311
P
T
S
S
R
Y
H
T
Y
L
P
P
P
Y
P
Tiger Blowfish
Takifugu rubipres
NP_001092121
407
44638
A299
I
S
G
L
S
M
S
A
S
S
R
Y
H
T
Y
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
H559
A
H
H
P
H
A
H
H
A
H
A
H
L
Q
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN1
302
31144
F195
V
S
T
A
Q
A
F
F
T
E
F
I
I
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
63
48.6
N.A.
91.5
59.5
N.A.
N.A.
68.9
56.9
68.1
67.9
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
68.2
56.1
N.A.
94.6
70.4
N.A.
N.A.
74.2
69
75.2
77.3
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
20
13.3
93.3
N.A.
6.6
20
N.A.
N.A.
6.6
0
13.3
6.6
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
20
93.3
N.A.
13.3
33.3
N.A.
N.A.
13.3
6.6
26.6
20
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
9
17
0
25
0
25
9
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% E
% Phe:
0
0
9
17
0
0
17
9
0
9
9
0
0
0
9
% F
% Gly:
9
0
9
0
0
0
0
0
0
9
0
0
0
9
25
% G
% His:
0
9
9
17
34
17
17
17
9
9
9
34
9
0
9
% H
% Ile:
9
0
0
0
0
9
0
0
0
0
0
9
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
9
9
0
0
0
9
17
9
0
9
9
0
17
% L
% Met:
17
9
0
9
9
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
9
0
17
9
0
0
0
25
25
34
34
25
34
17
% P
% Gln:
9
0
0
0
17
0
0
0
0
0
0
0
0
17
9
% Q
% Arg:
0
9
25
0
9
9
0
0
9
17
9
0
0
0
0
% R
% Ser:
9
34
25
17
25
0
34
9
9
9
0
0
0
9
0
% S
% Thr:
9
25
9
0
0
25
25
9
17
9
0
0
17
9
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
9
17
9
0
25
17
25
25
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _